BDBM50312713 (S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)phenyl)methyl)-2-isopropyl-7,7-dimethyl-5,6,7,8-tetrahydroquinolin-5-ol::CHEMBL1081287

SMILES: CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=LKISIMKAWPWFFM-OFVILXPXSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312713 ((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...) Show SMILES CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C28H35F4NO/c1-16(2)26-24(25(29)18-10-12-19(13-11-18)28(30,31)32)22(17-8-6-5-7-9-17)23-20(33-26)14-27(3,4)15-21(23)34/h10-13,16-17,21,25,34H,5-9,14-15H2,1-4H3/t21-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312713 ((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...) Show SMILES CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C28H35F4NO/c1-16(2)26-24(25(29)18-10-12-19(13-11-18)28(30,31)32)22(17-8-6-5-7-9-17)23-20(33-26)14-27(3,4)15-21(23)34/h10-13,16-17,21,25,34H,5-9,14-15H2,1-4H3/t21-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312713 ((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...) Show SMILES CC(C)c1nc2CC(C)(C)C[C@H](O)c2c(C2CCCCC2)c1[C@@H](F)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C28H35F4NO/c1-16(2)26-24(25(29)18-10-12-19(13-11-18)28(30,31)32)22(17-8-6-5-7-9-17)23-20(33-26)14-27(3,4)15-21(23)34/h10-13,16-17,21,25,34H,5-9,14-15H2,1-4H3/t21-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair