BDBM50312717 (S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(trifluoromethyl)benzyl)-5,6,7,8-tetrahydroquinolin-5-ol::CHEMBL1081307

SMILES: CC1(C)C[C@H](O)c2c(C1)nc(C1CCCC1)c(Cc1ccc(cc1)C(F)(F)F)c2C1CCCCC1

InChI Key: InChIKey=BBGDZXUCEYOTHB-VWLOTQADSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312717   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312717 ((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCCC1)c(Cc1ccc(cc1)C(F)(F)F)c2C1CCCCC1 |r| Show InChI InChI=1S/C30H38F3NO/c1-29(2)17-24-27(25(35)18-29)26(20-8-4-3-5-9-20)23(28(34-24)21-10-6-7-11-21)16-19-12-14-22(15-13-19)30(31,32)33/h12-15,20-21,25,35H,3-11,16-18H2,1-2H3/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312717 ((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...) Show SMILES CC1(C)C[C@H](O)c2c(C1)nc(C1CCCC1)c(Cc1ccc(cc1)C(F)(F)F)c2C1CCCCC1 |r| Show InChI InChI=1S/C30H38F3NO/c1-29(2)17-24-27(25(35)18-29)26(20-8-4-3-5-9-20)23(28(34-24)21-10-6-7-11-21)16-19-12-14-22(15-13-19)30(31,32)33/h12-15,20-21,25,35H,3-11,16-18H2,1-2H3/t25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair