BDBM50312722 (S)-(2'-cyclopentyl-5'-hydroxy-4'-propyl-6',8'-dihydro-5'H-spiro[cyclobutane-1,7'-quinoline]-3'-yl)(4-(trifluoromethyl)phenyl)methanone::CHEMBL1088039
SMILES: CCCc1c2[C@@H](O)CC3(CCC3)Cc2nc(C2CCCC2)c1C(=O)c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=MGJOFBAKSYLRPT-QFIPXVFZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholesteryl ester transfer protein (Homo sapiens (Human)) | BDBM50312722 ((S)-(2'-cyclopentyl-5'-hydroxy-4'-propyl-6',8'-dih...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare AG Curated by ChEMBL | Assay Description Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assay | Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P | |||||||||||
More data for this Ligand-Target Pair |