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BDBM50312828 1-(2,4-dichlorophenyl)-N-methyl-5-phenyl-N'-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazole-3-carboximidamide::CHEMBL1081306

SMILES: CN=C(NS(=O)(=O)c1ccc(cc1)C(F)(F)F)C1=NN(C(C1)c1ccccc1)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=KFUBUHJCBKCTEW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312828   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50312828
PNG
(1-(2,4-dichlorophenyl)-N-methyl-5-phenyl-N'-(4-(tr...)
Show SMILES CN=C(NS(=O)(=O)c1ccc(cc1)C(F)(F)F)C1=NN(C(C1)c1ccccc1)c1ccc(Cl)cc1Cl |w:1.0,t:18|
Show InChI InChI=1S/C24H19Cl2F3N4O2S/c1-30-23(32-36(34,35)18-10-7-16(8-11-18)24(27,28)29)20-14-22(15-5-3-2-4-6-15)33(31-20)21-12-9-17(25)13-19(21)26/h2-13,22H,14H2,1H3,(H,30,32)
PDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents

Article
PubMed
11.3n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB1 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 1752-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.049
BindingDB Entry DOI: 10.7270/Q2736RWV
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50312828
PNG
(1-(2,4-dichlorophenyl)-N-methyl-5-phenyl-N'-(4-(tr...)
Show SMILES CN=C(NS(=O)(=O)c1ccc(cc1)C(F)(F)F)C1=NN(C(C1)c1ccccc1)c1ccc(Cl)cc1Cl |w:1.0,t:18|
Show InChI InChI=1S/C24H19Cl2F3N4O2S/c1-30-23(32-36(34,35)18-10-7-16(8-11-18)24(27,28)29)20-14-22(15-5-3-2-4-6-15)33(31-20)21-12-9-17(25)13-19(21)26/h2-13,22H,14H2,1H3,(H,30,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
179n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from human cannabinoid CB2 receptor expressed in CHO cells


Bioorg Med Chem Lett 20: 1752-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.049
BindingDB Entry DOI: 10.7270/Q2736RWV
More data for this
Ligand-Target Pair