BDBM50313018 (Z)-4-(2-(2-chlorophenyl)hydrazono)-3-phenyl-1H-pyrazol-5(4H)-one::CHEMBL1080544

SMILES: Clc1ccccc1N=Nc1c([nH][nH]c1=O)-c1ccccc1

InChI Key: InChIKey=WKYWNCKMBOAMGK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313018 ((Z)-4-(2-(2-chlorophenyl)hydrazono)-3-phenyl-1H-py...) Show SMILES Clc1ccccc1N=Nc1c([nH][nH]c1=O)-c1ccccc1 |w:8.9| Show InChI InChI=1S/C15H11ClN4O/c16-11-8-4-5-9-12(11)17-19-14-13(18-20-15(14)21)10-6-2-1-3-7-10/h1-9H,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay				Bioorg Med Chem Lett 20: 1661-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.072 BindingDB Entry DOI: 10.7270/Q2TX3G9B
					More data for this Ligand-Target Pair