BDBM50313020 (Z)-4-(2-(2-chlorophenyl)hydrazono)-3-(pyridin-3-yl)-1H-pyrazol-5(4H)-one::CHEMBL1080376

SMILES: Clc1ccccc1N=Nc1c([nH][nH]c1=O)-c1cccnc1

InChI Key: InChIKey=DBLNZDPVDYTIQA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313020 ((Z)-4-(2-(2-chlorophenyl)hydrazono)-3-(pyridin-3-y...) Show SMILES Clc1ccccc1N=Nc1c([nH][nH]c1=O)-c1cccnc1 |w:8.9| Show InChI InChI=1S/C14H10ClN5O/c15-10-5-1-2-6-11(10)17-19-13-12(18-20-14(13)21)9-4-3-7-16-8-9/h1-8H,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay				Bioorg Med Chem Lett 20: 1661-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.072 BindingDB Entry DOI: 10.7270/Q2TX3G9B
					More data for this Ligand-Target Pair