BDBM50313028 (Z)-4-(2-(3-methoxyphenyl)hydrazono)-3-phenyl-1H-pyrazol-5(4H)-one::CHEMBL1081278

SMILES: COc1cccc(c1)N=Nc1c([nH][nH]c1=O)-c1ccccc1

InChI Key: InChIKey=LQRGKLDKPBGOAX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313028 ((Z)-4-(2-(3-methoxyphenyl)hydrazono)-3-phenyl-1H-p...) Show SMILES COc1cccc(c1)N=Nc1c([nH][nH]c1=O)-c1ccccc1 |w:9.10| Show InChI InChI=1S/C16H14N4O2/c1-22-13-9-5-8-12(10-13)17-19-15-14(18-20-16(15)21)11-6-3-2-4-7-11/h2-10H,1H3,(H2,18,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay				Bioorg Med Chem Lett 20: 1661-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.072 BindingDB Entry DOI: 10.7270/Q2TX3G9B
					More data for this Ligand-Target Pair