BDBM50313058 (Z)-3-(3,4-dimethoxyphenyl)-4-(2-(4-(dimethylamino)phenyl)hydrazono)-1H-pyrazol-5(4H)-one::CHEMBL1086601

SMILES: COc1ccc(cc1OC)-c1[nH][nH]c(=O)c1N=Nc1ccc(cc1)N(C)C

InChI Key: InChIKey=HPWUVSNGQZOJJR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313058   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50313058 ((Z)-3-(3,4-dimethoxyphenyl)-4-(2-(4-(dimethylamino...) Show SMILES COc1ccc(cc1OC)-c1[nH][nH]c(=O)c1N=Nc1ccc(cc1)N(C)C |w:16.17| Show InChI InChI=1S/C19H21N5O3/c1-24(2)14-8-6-13(7-9-14)20-22-18-17(21-23-19(18)25)12-5-10-15(26-3)16(11-12)27-4/h5-11H,1-4H3,(H2,21,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vertex Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of GSK3-beta assessed as NADH level after 10 mins by pyruvate kinase/lactate dehydrogenase coupled spectrophotometric assay				Bioorg Med Chem Lett 20: 1661-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.072 BindingDB Entry DOI: 10.7270/Q2TX3G9B
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