BDBM50313170 2-(1-ethyl-3-methyl-4-(4-methylphenethyl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)-N-methyl-2-phenylacetamide::CHEMBL1080686

SMILES: CCn1nc(C)c2C(CCc3ccc(C)cc3)N(CCc12)C(C(=O)NC)c1ccccc1

InChI Key: InChIKey=YVQBKJZIAAENQZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM50313170 (2-(1-ethyl-3-methyl-4-(4-methylphenethyl)-6,7-dihy...) Show SMILES CCn1nc(C)c2C(CCc3ccc(C)cc3)N(CCc12)C(C(=O)NC)c1ccccc1 Show InChI InChI=1S/C27H34N4O/c1-5-31-24-17-18-30(26(27(32)28-4)22-9-7-6-8-10-22)23(25(24)20(3)29-31)16-15-21-13-11-19(2)12-14-21/h6-14,23,26H,5,15-18H2,1-4H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Antagonist activity at human OX2 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 20: 1539-42 (2010) Article DOI: 10.1016/j.bmcl.2010.01.070 BindingDB Entry DOI: 10.7270/Q2FB5324
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM50313170 (2-(1-ethyl-3-methyl-4-(4-methylphenethyl)-6,7-dihy...) Show SMILES CCn1nc(C)c2C(CCc3ccc(C)cc3)N(CCc12)C(C(=O)NC)c1ccccc1 Show InChI InChI=1S/C27H34N4O/c1-5-31-24-17-18-30(26(27(32)28-4)22-9-7-6-8-10-22)23(25(24)20(3)29-31)16-15-21-13-11-19(2)12-14-21/h6-14,23,26H,5,15-18H2,1-4H3,(H,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 20: 1539-42 (2010) Article DOI: 10.1016/j.bmcl.2010.01.070 BindingDB Entry DOI: 10.7270/Q2FB5324
					More data for this Ligand-Target Pair