BDBM50313314 6-(cyclopropylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide::CHEMBL1081080

SMILES: Cc1cc(O)ccc1NC(=O)c1cc(NC2CC2)ncn1

InChI Key: InChIKey=YPFNIUYRUIDNJX-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50313314 (6-(cyclopropylamino)-N-(4-hydroxy-2-methylphenyl)p...) Show SMILES Cc1cc(O)ccc1NC(=O)c1cc(NC2CC2)ncn1 Show InChI InChI=1S/C15H16N4O2/c1-9-6-11(20)4-5-12(9)19-15(21)13-7-14(17-8-16-13)18-10-2-3-10/h4-8,10,20H,2-3H2,1H3,(H,19,21)(H,16,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assay				Bioorg Med Chem Lett 20: 1516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.102 BindingDB Entry DOI: 10.7270/Q2J38SQK
					More data for this Ligand-Target Pair