BDBM50313348 6-(cyclohexylamino)-N-(1H-indol-5-yl)pyrimidine-4-carboxamide::CHEMBL1080685

SMILES: O=C(Nc1ccc2[nH]ccc2c1)c1cc(NC2CCCCC2)ncn1

InChI Key: InChIKey=XOEUJDNRYAEWRB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50313348 (6-(cyclohexylamino)-N-(1H-indol-5-yl)pyrimidine-4-...) Show SMILES O=C(Nc1ccc2[nH]ccc2c1)c1cc(NC2CCCCC2)ncn1 Show InChI InChI=1S/C19H21N5O/c25-19(24-15-6-7-16-13(10-15)8-9-20-16)17-11-18(22-12-21-17)23-14-4-2-1-3-5-14/h6-12,14,20H,1-5H2,(H,24,25)(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a
Merck Serono SA Curated by ChEMBL					Assay Description Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assay				Bioorg Med Chem Lett 20: 1516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.102 BindingDB Entry DOI: 10.7270/Q2J38SQK
					More data for this Ligand-Target Pair