BDBM50313372 (3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)phenyl)-2,2-bis(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol::CHEMBL1094713

SMILES: COc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(CO)(CO)[C@@H](O)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=VDTAFRVZXXUACU-ZRNYENFQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50313372 ((3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)pheny...) Show SMILES COc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(CO)(CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H25ClO7/c1-28-15-5-2-12(3-6-15)8-14-9-13(4-7-16(14)22)19-17(25)18(26)20(27)21(10-23,11-24)29-19/h2-7,9,17-20,23-27H,8,10-11H2,1H3/t17-,18-,19+,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs				Bioorg Med Chem Lett 20: 1569-72 (2010) Article DOI: 10.1016/j.bmcl.2010.01.075 BindingDB Entry DOI: 10.7270/Q2DF6RBP
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50313372 ((3S,4R,5R,6S)-6-(4-chloro-3-(4-methoxybenzyl)pheny...) Show SMILES COc1ccc(Cc2cc(ccc2Cl)[C@@H]2OC(CO)(CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H25ClO7/c1-28-15-5-2-12(3-6-15)8-14-9-13(4-7-16(14)22)19-17(25)18(26)20(27)21(10-23,11-24)29-19/h2-7,9,17-20,23-27H,8,10-11H2,1H3/t17-,18-,19+,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research& Development Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of sodium-dependent methyl-alpha-D-[U-14C]glucopyranoside uptake after 2 hrs				Bioorg Med Chem Lett 20: 1569-72 (2010) Article DOI: 10.1016/j.bmcl.2010.01.075 BindingDB Entry DOI: 10.7270/Q2DF6RBP
					More data for this Ligand-Target Pair