BDBM50313446 CHEMBL1096003::N-(((2R,4aS,5R,10bS)-9-chloro-7-fluoro-5-phenyl-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinolin-2-yl)methyl)-2-(dimethylamino)ethanesulfonamide

SMILES: CN(C)CCS(=O)(=O)NC[C@H]1CC[C@H]2[C@@H](Nc3c(F)cc(Cl)cc3[C@H]2O1)c1ccccc1

InChI Key: InChIKey=XNXPMZDKAOHHSM-GPFNJZLUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50313446 (CHEMBL1096003 | N-(((2R,4aS,5R,10bS)-9-chloro-7-fl...) Show SMILES CN(C)CCS(=O)(=O)NC[C@H]1CC[C@H]2[C@@H](Nc3c(F)cc(Cl)cc3[C@H]2O1)c1ccccc1 |r| Show InChI InChI=1S/C23H29ClFN3O3S/c1-28(2)10-11-32(29,30)26-14-17-8-9-18-21(15-6-4-3-5-7-15)27-22-19(23(18)31-17)12-16(24)13-20(22)25/h3-7,12-13,17-18,21,23,26-27H,8-11,14H2,1-2H3/t17-,18+,21+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of ATPase activity of human recombinant EG5 assessed as ATP hydrolysis by pyruvate kinase-lactate dehydrogenase coupled assay				Bioorg Med Chem Lett 20: 1491-5 (2010) Article DOI: 10.1016/j.bmcl.2010.01.110 BindingDB Entry DOI: 10.7270/Q2KD1ZWN
					More data for this Ligand-Target Pair