BDBM50313578 (E)-5-(4-((4-(dimethylamino)piperidin-1-yl)methyl)styryl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL1088056

SMILES: CN(C)C1CCN(Cc2ccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)cc2)CC1

InChI Key: InChIKey=XEHZTUCPROUDNJ-CMDGGOBGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50313578 ((E)-5-(4-((4-(dimethylamino)piperidin-1-yl)methyl)...) Show SMILES CN(C)C1CCN(Cc2ccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)cc2)CC1 Show InChI InChI=1S/C31H34N6/c1-22-28-12-15-34-30(28)11-10-29(22)35-31-25(19-33-20-26(31)18-32)9-8-23-4-6-24(7-5-23)21-37-16-13-27(14-17-37)36(2)3/h4-12,15,19-20,27,34H,13-14,16-17,21H2,1-3H3,(H,33,35)/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50313578 ((E)-5-(4-((4-(dimethylamino)piperidin-1-yl)methyl)...) Show SMILES CN(C)C1CCN(Cc2ccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)cc2)CC1 Show InChI InChI=1S/C31H34N6/c1-22-28-12-15-34-30(28)11-10-29(22)35-31-25(19-33-20-26(31)18-32)9-8-23-4-6-24(7-5-23)21-37-16-13-27(14-17-37)36(2)3/h4-12,15,19-20,27,34H,13-14,16-17,21H2,1-3H3,(H,33,35)/b9-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair