BDBM50313582 (E)-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(morpholinomethyl)styryl)nicotinonitrile::CHEMBL1086419

SMILES: Cc1c(Nc2c(\C=C\c3cccc(CN4CCOCC4)c3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=FPSGCBWWRUZTIV-AATRIKPKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50313582 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(morpholi...) Show SMILES Cc1c(Nc2c(\C=C\c3cccc(CN4CCOCC4)c3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H27N5O/c1-20-25-9-10-31-27(25)8-7-26(20)32-28-23(17-30-18-24(28)16-29)6-5-21-3-2-4-22(15-21)19-33-11-13-34-14-12-33/h2-10,15,17-18,31H,11-14,19H2,1H3,(H,30,32)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50313582 ((E)-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(morpholi...) Show SMILES Cc1c(Nc2c(\C=C\c3cccc(CN4CCOCC4)c3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H27N5O/c1-20-25-9-10-31-27(25)8-7-26(20)32-28-23(17-30-18-24(28)16-29)6-5-21-3-2-4-22(15-21)19-33-11-13-34-14-12-33/h2-10,15,17-18,31H,11-14,19H2,1H3,(H,30,32)/b6-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair