BDBM50313596 (E)-5-(2-(6-((4-(dimethylamino)piperidin-1-yl)methyl)pyridin-2-yl)vinyl)-4-(4-methyl-1H-indol-5-ylamino)nicotinonitrile::CHEMBL1088737

SMILES: CN(C)C1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1

InChI Key: InChIKey=ICQQDVZUHPTFPS-BQYQJAHWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50313596 ((E)-5-(2-(6-((4-(dimethylamino)piperidin-1-yl)meth...) Show SMILES CN(C)C1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1 Show InChI InChI=1S/C30H33N7/c1-21-27-11-14-33-29(27)10-9-28(21)35-30-22(18-32-19-23(30)17-31)7-8-24-5-4-6-25(34-24)20-37-15-12-26(13-16-37)36(2)3/h4-11,14,18-19,26,33H,12-13,15-16,20H2,1-3H3,(H,32,35)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50313596 ((E)-5-(2-(6-((4-(dimethylamino)piperidin-1-yl)meth...) Show SMILES CN(C)C1CCN(Cc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)n2)CC1 Show InChI InChI=1S/C30H33N7/c1-21-27-11-14-33-29(27)10-9-28(21)35-30-22(18-32-19-23(30)17-31)7-8-24-5-4-6-25(34-24)20-37-15-12-26(13-16-37)36(2)3/h4-11,14,18-19,26,33H,12-13,15-16,20H2,1-3H3,(H,32,35)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 20: 1965-8 (2010) Article DOI: 10.1016/j.bmcl.2010.01.119 BindingDB Entry DOI: 10.7270/Q2H70FX5
					More data for this Ligand-Target Pair