BDBM50313607 5'-Chloro-7'-methyl-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL1095686
SMILES: Cc1cc(Cl)cc2C(C(=O)Nc12)c1[nH]c2ccccc2c1N=O
InChI Key: InChIKey=IIASNOJFHRNMQV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human)) | BDBM50313607 (5'-Chloro-7'-methyl-1H,1'H-[2,3']biindolylidene-3,...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology Curated by ChEMBL | Assay Description Inhibition of FLT3 by HTRF assay | Bioorg Med Chem Lett 20: 2033-7 (2010) Article DOI: 10.1016/j.bmcl.2010.01.039 BindingDB Entry DOI: 10.7270/Q29W0GF0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 17B (STK17B) (Homo sapiens (Human)) | BDBM50313607 (5'-Chloro-7'-methyl-1H,1'H-[2,3']biindolylidene-3,...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assay | Bioorg Med Chem Lett 26: 2719-23 (2016) Article DOI: 10.1016/j.bmcl.2016.03.111 BindingDB Entry DOI: 10.7270/Q2N29ZTZ | |||||||||||
More data for this Ligand-Target Pair |