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BDBM50313608 5',7'-Dimethyl-1H,1'H-[2,3']biindolylidene-3,2'-dione 3-oxime::CHEMBL1095374

SMILES: Cc1cc2C(C(=O)Nc2c(C)c1)c1[nH]c2ccccc2c1N=O

InChI Key: InChIKey=ULVANNSGZPDTMM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313608   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50313608
PNG
(5',7'-Dimethyl-1H,1'H-[2,3']biindolylidene-3,2'-di...)
Show SMILES Cc1cc2C(C(=O)Nc2c(C)c1)c1[nH]c2ccccc2c1N=O
Show InChI InChI=1S/C18H15N3O2/c1-9-7-10(2)15-12(8-9)14(18(22)20-15)17-16(21-23)11-5-3-4-6-13(11)19-17/h3-8,14,19H,1-2H3,(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 952n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of FLT3 by HTRF assay


Bioorg Med Chem Lett 20: 2033-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.039
BindingDB Entry DOI: 10.7270/Q29W0GF0
More data for this
Ligand-Target Pair