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BDBM50313617 1-Acetyl-1H,1'H-[2,3']biindolylidene-3,2'-dione::CHEMBL1085921

SMILES: CC(=O)N1\C(C(=O)c2ccccc12)=C1/C(=O)Nc2ccccc12

InChI Key: InChIKey=BWCDBDQTFLQAGD-NXVVXOECSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313617   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Receptor-type tyrosine-protein kinase FLT3


(Homo sapiens (Human))
BDBM50313617
PNG
(1-Acetyl-1H,1'H-[2,3']biindolylidene-3,2'-dione | ...)
Show SMILES CC(=O)N1\C(C(=O)c2ccccc12)=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C18H12N2O3/c1-10(21)20-14-9-5-3-7-12(14)17(22)16(20)15-11-6-2-4-8-13(11)19-18(15)23/h2-9H,1H3,(H,19,23)/b16-15-
PDB
MMDB

KEGG

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Institute of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of FLT3 by HTRF assay


Bioorg Med Chem Lett 20: 2033-7 (2010)


Article DOI: 10.1016/j.bmcl.2010.01.039
BindingDB Entry DOI: 10.7270/Q29W0GF0
More data for this
Ligand-Target Pair