BDBM50314048 CHEMBL1089410::N-(3-(2-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES: FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1cccs1

InChI Key: InChIKey=ARMKBDOVOBCACP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50314048 (CHEMBL1089410 | N-(3-(2-(thiophen-2-yl)pyrazolo[1,...) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1cccs1 Show InChI InChI=1S/C24H15F3N4OS/c25-24(26,27)17-6-1-5-16(12-17)23(32)29-18-7-2-4-15(13-18)20-9-10-28-22-14-19(30-31(20)22)21-8-3-11-33-21/h1-14H,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 19: 6890-2 (2009) Article DOI: 10.1016/j.bmcl.2009.10.074 BindingDB Entry DOI: 10.7270/Q2C829F3
					More data for this Ligand-Target Pair