BDBM50314055 CHEMBL1093105::N-(3-(2-morpholinopyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

SMILES: FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)N1CCOCC1

InChI Key: InChIKey=CSBJRBYRFSOSAV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50314055 (CHEMBL1093105 | N-(3-(2-morpholinopyrazolo[1,5-a]p...) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)N1CCOCC1 Show InChI InChI=1S/C24H20F3N5O2/c25-24(26,27)18-5-1-4-17(13-18)23(33)29-19-6-2-3-16(14-19)20-7-8-28-21-15-22(30-32(20)21)31-9-11-34-12-10-31/h1-8,13-15H,9-12H2,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 19: 6890-2 (2009) Article DOI: 10.1016/j.bmcl.2009.10.074 BindingDB Entry DOI: 10.7270/Q2C829F3
					More data for this Ligand-Target Pair