BDBM50314056 3-chloro-N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)benzamide::CHEMBL1089751

SMILES: Clc1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1ccncc1

InChI Key: InChIKey=XOPKUUJHGXTLIH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50314056 (3-chloro-N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyri...) Show SMILES Clc1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1ccncc1 Show InChI InChI=1S/C24H16ClN5O/c25-19-5-1-4-18(13-19)24(31)28-20-6-2-3-17(14-20)22-9-12-27-23-15-21(29-30(22)23)16-7-10-26-11-8-16/h1-15H,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 19: 6890-2 (2009) Article DOI: 10.1016/j.bmcl.2009.10.074 BindingDB Entry DOI: 10.7270/Q2C829F3
					More data for this Ligand-Target Pair