BDBM50314059 4-chloro-N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide::CHEMBL1090083

SMILES: FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1ccncc1

InChI Key: InChIKey=NAZBCPATAWKFPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50314059 (4-chloro-N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyri...) Show SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1ccncc1 Show InChI InChI=1S/C25H15ClF3N5O/c26-20-5-4-17(13-19(20)25(27,28)29)24(35)32-18-3-1-2-16(12-18)22-8-11-31-23-14-21(33-34(22)23)15-6-9-30-10-7-15/h1-14H,(H,32,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of b-Raf				Bioorg Med Chem Lett 19: 6890-2 (2009) Article DOI: 10.1016/j.bmcl.2009.10.074 BindingDB Entry DOI: 10.7270/Q2C829F3
					More data for this Ligand-Target Pair