BDBM50314113 1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)furo[2,3-b]pyridin-2-yl)-2-methylpropan-1-one::CHEMBL1091692
SMILES: CC(C)C(=O)c1oc2nc(-c3ccccc3Cl)c(cc2c1N)-c1ccc(Cl)cc1
InChI Key: InChIKey=DMOWIFGXQZDDEZ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50314113 (1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human CB2 receptor | Bioorg Med Chem Lett 20: 1448-52 (2010) Article DOI: 10.1016/j.bmcl.2009.12.065 BindingDB Entry DOI: 10.7270/Q2028RPD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50314113 (1-(3-amino-6-(2-chlorophenyl)-5-(4-chlorophenyl)fu...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human CB1 receptor | Bioorg Med Chem Lett 20: 1448-52 (2010) Article DOI: 10.1016/j.bmcl.2009.12.065 BindingDB Entry DOI: 10.7270/Q2028RPD | |||||||||||
More data for this Ligand-Target Pair |