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SMILES: OC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C/C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1

InChI Key: InChIKey=JZPWDKFPBDFFKJ-OVRDARLSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cysteine protease


(Trypanosoma brucei rhodesiense)		BDBM50314126
PNG
((S)-Benzyl-2-[(Z)-3-((S)-1-benzyloxycarbonyl-2-phe...)
Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C/C(=O)N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C29H28N2O6/c32-26(30-24(28(34)35)18-21-10-4-1-5-11-21)16-17-27(33)31-25(19-22-12-6-2-7-13-22)29(36)37-20-23-14-8-3-9-15-23/h1-17,24-25H,18-20H2,(H,30,32)(H,31,33)(H,34,35)/b17-16-/t24-,25-/m0/s1
PDB
MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
Article
PubMed
 150n/an/an/an/an/an/an/an/a



University of W£rzburg

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma brucei rhodesiense recombinant rhodesain by standard fluorescence assay

J Med Chem 53: 1951-63 (2010)


Article DOI: 10.1021/jm900946n
BindingDB Entry DOI: 10.7270/Q2V9887Z
More data for this
Ligand-Target Pair