Found 4 hits for monomerid = 50314290 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50314290
(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)Show SMILES Brc1ccc(cc1)N(C1CCN(Cc2ccncc2)CC1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H27BrN4O/c26-22-6-8-23(9-7-22)30(25(31)28-18-20-4-2-1-3-5-20)24-12-16-29(17-13-24)19-21-10-14-27-15-11-21/h1-11,14-15,24H,12-13,16-19H2,(H,28,31) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Antagonist activity at human recombinant histamine 3 receptor |
Bioorg Med Chem Lett 20: 2359-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.121 BindingDB Entry DOI: 10.7270/Q2Z31ZSM |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50314290
(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)Show SMILES Brc1ccc(cc1)N(C1CCN(Cc2ccncc2)CC1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H27BrN4O/c26-22-6-8-23(9-7-22)30(25(31)28-18-20-4-2-1-3-5-20)24-12-16-29(17-13-24)19-21-10-14-27-15-11-21/h1-11,14-15,24H,12-13,16-19H2,(H,28,31) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bioprojet-Biotech
Curated by ChEMBL
| Assay Description Displacement of [125I]Iodoproxyfan from human recombinant histamine H3 receptor by Competitive binding assay |
Bioorg Med Chem Lett 21: 5378-83 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.006 BindingDB Entry DOI: 10.7270/Q2VX0GXK |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50314290
(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)Show SMILES Brc1ccc(cc1)N(C1CCN(Cc2ccncc2)CC1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H27BrN4O/c26-22-6-8-23(9-7-22)30(25(31)28-18-20-4-2-1-3-5-20)24-12-16-29(17-13-24)19-21-10-14-27-15-11-21/h1-11,14-15,24H,12-13,16-19H2,(H,28,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bioprojet-Biotech
Curated by ChEMBL
| Assay Description Displacement of [3H]dofetilide from human recombinant ERG by Competitive binding assay |
Bioorg Med Chem Lett 21: 5378-83 (2011)
Article DOI: 10.1016/j.bmcl.2011.07.006 BindingDB Entry DOI: 10.7270/Q2VX0GXK |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50314290
(3-benzyl-1-(4-bromophenyl)-1-(1-(pyridin-4-ylmethy...)Show SMILES Brc1ccc(cc1)N(C1CCN(Cc2ccncc2)CC1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C25H27BrN4O/c26-22-6-8-23(9-7-22)30(25(31)28-18-20-4-2-1-3-5-20)24-12-16-29(17-13-24)19-21-10-14-27-15-11-21/h1-11,14-15,24H,12-13,16-19H2,(H,28,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human ERG by ion works assay |
Bioorg Med Chem Lett 20: 2359-64 (2010)
Article DOI: 10.1016/j.bmcl.2010.01.121 BindingDB Entry DOI: 10.7270/Q2Z31ZSM |
More data for this Ligand-Target Pair | |