BDBM50314420 3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carboxamide::CHEMBL1091830
SMILES: Cc1ccsc1-c1c2CCCCCCc2nc2sc(C(N)=O)c(N)c12
InChI Key: InChIKey=JFWUTNVXUNPNJU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Eukaryotic elongation factor 2 kinase (Homo sapiens (Human)) | BDBM50314420 (3-amino-4-(3-methylthiophen-2-yl)-5,6,7,8,9,10-hex...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Myriad Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of GST tagged eEf2K expressed in Escherichia coli by fluorometric method | Bioorg Med Chem Lett 20: 2283-6 (2010) Article DOI: 10.1016/j.bmcl.2010.02.005 BindingDB Entry DOI: 10.7270/Q2F18ZVT | |||||||||||
More data for this Ligand-Target Pair |