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BDBM50314515 CHEMBL1093776::N-ethyl-N-(6-methoxypyridin-3-yl)-3-p-tolyl-1H-pyrazole-5-carboxamide

SMILES: CCN(C(=O)c1cc(n[nH]1)-c1ccc(C)cc1)c1ccc(OC)nc1

InChI Key: InChIKey=BQCOSURMPNVNKW-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314515   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oxytocin receptor


(HEK293)
BDBM50314515
PNG
(CHEMBL1093776 | N-ethyl-N-(6-methoxypyridin-3-yl)-...)
Show SMILES CCN(C(=O)c1cc(n[nH]1)-c1ccc(C)cc1)c1ccc(OC)nc1
Show InChI InChI=1S/C19H20N4O2/c1-4-23(15-9-10-18(25-3)20-12-15)19(24)17-11-16(21-22-17)14-7-5-13(2)6-8-14/h5-12H,4H2,1-3H3,(H,21,22)
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KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
41n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human cloned OT receptor by cell based beta-lactamase reporter gene assay


Bioorg Med Chem Lett 20: 2224-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.018
BindingDB Entry DOI: 10.7270/Q2X34XMS
More data for this
Ligand-Target Pair