null

SMILES: Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ncccn3)nnc(-c3cccc(Cl)c3)c2n1C

InChI Key: InChIKey=NTTHGUAFUATIQR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50314573 ((4-(3-(7-(3-chlorophenyl)-1,2-dimethyl-1H-pyrrolo[...) Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ncccn3)nnc(-c3cccc(Cl)c3)c2n1C Show InChI InChI=1S/C26H29ClN8O/c1-18-16-21-23(33(18)2)22(19-6-3-7-20(27)17-19)31-32-24(21)28-10-5-11-34-12-14-35(15-13-34)26(36)25-29-8-4-9-30-25/h3-4,6-9,16-17H,5,10-15H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting				Bioorg Med Chem Lett 20: 2163-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.044 BindingDB Entry DOI: 10.7270/Q2NK3F54
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50314573 ((4-(3-(7-(3-chlorophenyl)-1,2-dimethyl-1H-pyrrolo[...) Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ncccn3)nnc(-c3cccc(Cl)c3)c2n1C Show InChI InChI=1S/C26H29ClN8O/c1-18-16-21-23(33(18)2)22(19-6-3-7-20(27)17-19)31-32-24(21)28-10-5-11-34-12-14-35(15-13-34)26(36)25-29-8-4-9-30-25/h3-4,6-9,16-17H,5,10-15H2,1-2H3,(H,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation counting				Bioorg Med Chem Lett 20: 2163-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.044 BindingDB Entry DOI: 10.7270/Q2NK3F54
					More data for this Ligand-Target Pair