BDBM50314582 (4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3,2-d]pyridazin-4-ylamino)propyl)piperazin-1-yl)(pyridazin-4-yl)methanone::CHEMBL1090405

SMILES: Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ccnnc3)nnc(-c3cccc(c3)[N+]([O-])=O)c2n1C

InChI Key: InChIKey=NZAKJLXLGGYYCX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50314582 ((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...) Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ccnnc3)nnc(-c3cccc(c3)[N+]([O-])=O)c2n1C Show InChI InChI=1S/C26H29N9O3/c1-18-15-22-24(32(18)2)23(19-5-3-6-21(16-19)35(37)38)30-31-25(22)27-8-4-10-33-11-13-34(14-12-33)26(36)20-7-9-28-29-17-20/h3,5-7,9,15-17H,4,8,10-14H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation counting				Bioorg Med Chem Lett 20: 2163-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.044 BindingDB Entry DOI: 10.7270/Q2NK3F54
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50314582 ((4-(3-(1,2-dimethyl-7-(3-nitrophenyl)-1H-pyrrolo[3...) Show SMILES Cc1cc2c(NCCCN3CCN(CC3)C(=O)c3ccnnc3)nnc(-c3cccc(c3)[N+]([O-])=O)c2n1C Show InChI InChI=1S/C26H29N9O3/c1-18-15-22-24(32(18)2)23(19-5-3-6-21(16-19)35(37)38)30-31-25(22)27-8-4-10-33-11-13-34(14-12-33)26(36)20-7-9-28-29-17-20/h3,5-7,9,15-17H,4,8,10-14H2,1-2H3,(H,27,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.12E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [methyl-3H]rolipram from PDE4D4 expressed in CHO cells after 1 hr by scintillation counting				Bioorg Med Chem Lett 20: 2163-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.044 BindingDB Entry DOI: 10.7270/Q2NK3F54
					More data for this Ligand-Target Pair