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SMILES: FC(F)(F)Oc1ccc(CNC(=O)[C@@H]2CCCN2)cc1

InChI Key: InChIKey=IRAQBRPOZKDHKB-NSHDSACASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50314620 ((S)-N-(4-(trifluoromethoxy)benzyl)pyrrolidine-2-ca...) Show SMILES FC(F)(F)Oc1ccc(CNC(=O)[C@@H]2CCCN2)cc1 |r| Show InChI InChI=1S/C13H15F3N2O2/c14-13(15,16)20-10-5-3-9(4-6-10)8-18-12(19)11-2-1-7-17-11/h3-6,11,17H,1-2,7-8H2,(H,18,19)/t11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to 5HT2C receptor				Bioorg Med Chem Lett 20: 2365-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.107 BindingDB Entry DOI: 10.7270/Q24M94QJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50314620 ((S)-N-(4-(trifluoromethoxy)benzyl)pyrrolidine-2-ca...) Show SMILES FC(F)(F)Oc1ccc(CNC(=O)[C@@H]2CCCN2)cc1 |r| Show InChI InChI=1S/C13H15F3N2O2/c14-13(15,16)20-10-5-3-9(4-6-10)8-18-12(19)11-2-1-7-17-11/h3-6,11,17H,1-2,7-8H2,(H,18,19)/t11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to 5HT2B receptor				Bioorg Med Chem Lett 20: 2365-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.107 BindingDB Entry DOI: 10.7270/Q24M94QJ
					More data for this Ligand-Target Pair