BDBM50314639 (E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piperidin-1-ylmethyl]phenyl}-N-hydroxyacrylamide::CHEMBL1093052

SMILES: ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c([nH]c3ccccc23)-c2ccccc2)c(F)c1

InChI Key: InChIKey=WACGNBTYNJLDBB-FYWRMAATSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314639   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50314639 ((E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piper...) Show SMILES ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c([nH]c3ccccc23)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C29H28FN3O2/c30-25-17-20(13-15-27(34)32-35)12-14-22(25)18-33-16-6-9-23(19-33)28-24-10-4-5-11-26(24)31-29(28)21-7-2-1-3-8-21/h1-5,7-8,10-15,17,23,31,35H,6,9,16,18-19H2,(H,32,34)/b15-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of FLAG-tagged HDAC1 expressed in HEK293 cells by fluorescent assay				J Med Chem 53: 2952-63 (2010) Article DOI: 10.1021/jm100007m BindingDB Entry DOI: 10.7270/Q20V8CZC
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50314639 ((E)-3-{3-Fluoro-4-[3-(2-phenyl-1H-indol-3-yl)piper...) Show SMILES ONC(=O)\C=C\c1ccc(CN2CCCC(C2)c2c([nH]c3ccccc23)-c2ccccc2)c(F)c1 Show InChI InChI=1S/C29H28FN3O2/c30-25-17-20(13-15-27(34)32-35)12-14-22(25)18-33-16-6-9-23(19-33)28-24-10-4-5-11-26(24)31-29(28)21-7-2-1-3-8-21/h1-5,7-8,10-15,17,23,31,35H,6,9,16,18-19H2,(H,32,34)/b15-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in CHO cells by automated patch clamp electrophisiology assay				J Med Chem 53: 2952-63 (2010) Article DOI: 10.1021/jm100007m BindingDB Entry DOI: 10.7270/Q20V8CZC
					More data for this Ligand-Target Pair