BDBM50314880 CHEMBL1089542::N-(3-(guanidinomethyl)benzyl)-N-(1-phenethylpiperidin-4-yl)propionamide
SMILES: [#6]-[#6]-[#6](=O)-[#7](-[#6]-c1cccc(-[#6]\[#7]=[#6](\[#7])-[#7])c1)-[#6]-1-[#6]-[#6]-[#7](-[#6]-[#6]-c2ccccc2)-[#6]-[#6]-1
InChI Key: InChIKey=AQTLLNFIIZDSEL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50314880 (CHEMBL1089542 | N-(3-(guanidinomethyl)benzyl)-N-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.448 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clinical Research Institute of Montreal Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane | J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50314880 (CHEMBL1089542 | N-(3-(guanidinomethyl)benzyl)-N-(1...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.536 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clinical Research Institute of Montreal Curated by ChEMBL | Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane | J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50314880 (CHEMBL1089542 | N-(3-(guanidinomethyl)benzyl)-N-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 43.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Clinical Research Institute of Montreal Curated by ChEMBL | Assay Description Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane | J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (MOUSE) | BDBM50314880 (CHEMBL1089542 | N-(3-(guanidinomethyl)benzyl)-N-(1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Clinical Research Institute of Montreal Curated by ChEMBL | Assay Description Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (GUINEA PIG) | BDBM50314880 (CHEMBL1089542 | N-(3-(guanidinomethyl)benzyl)-N-(1...) | UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Clinical Research Institute of Montreal Curated by ChEMBL | Assay Description Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction | J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R | |||||||||||
More data for this Ligand-Target Pair |