BDBM50314883 CHEMBL1089546::N-(3-Methylbenzyl)-N-(1-phenylethylpiperidine-4-yl)propionamide

SMILES: CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1

InChI Key: InChIKey=MZSFZQSYRHNECT-UHFFFAOYSA-N

Data: 3 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50314883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50314883 (CHEMBL1089546 | N-(3-Methylbenzyl)-N-(1-phenylethy...) Show SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	96	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane				J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50314883 (CHEMBL1089546 | N-(3-Methylbenzyl)-N-(1-phenylethy...) Show SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membrane				J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R
					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50314883 (CHEMBL1089546 | N-(3-Methylbenzyl)-N-(1-phenylethy...) Show SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane				J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50314883 (CHEMBL1089546 | N-(3-Methylbenzyl)-N-(1-phenylethy...) Show SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	647	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction				J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50314883 (CHEMBL1089546 | N-(3-Methylbenzyl)-N-(1-phenylethy...) Show SMILES CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C24H32N2O/c1-3-24(27)26(19-22-11-7-8-20(2)18-22)23-13-16-25(17-14-23)15-12-21-9-5-4-6-10-21/h4-11,18,23H,3,12-17,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
Clinical Research Institute of Montreal Curated by ChEMBL					Assay Description Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction				J Med Chem 53: 2875-81 (2010) Article DOI: 10.1021/jm9019068 BindingDB Entry DOI: 10.7270/Q21G0N7R
					More data for this Ligand-Target Pair