BDBM50314901 5-methoxy-1'-(2-(1-methyl-1H-pyrazol-3-yl)-1H-benzo[d]imidazole-5-carbonyl)spiro[chroman-2,4'-piperidin]-4-one::CHEMBL1093185

SMILES: COc1cccc2OC3(CCN(CC3)C(=O)c3ccc4nc([nH]c4c3)-c3ccn(C)n3)CC(=O)c12

InChI Key: InChIKey=MEQNAJYNVYVHAU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 1 (ACC1) (Rattus norvegicus (Rat))	BDBM50314901 (5-methoxy-1'-(2-(1-methyl-1H-pyrazol-3-yl)-1H-benz...) Show SMILES COc1cccc2OC3(CCN(CC3)C(=O)c3ccc4nc([nH]c4c3)-c3ccn(C)n3)CC(=O)c12 Show InChI InChI=1S/C26H25N5O4/c1-30-11-8-18(29-30)24-27-17-7-6-16(14-19(17)28-24)25(33)31-12-9-26(10-13-31)15-20(32)23-21(34-2)4-3-5-22(23)35-26/h3-8,11,14H,9-10,12-13,15H2,1-2H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of rat liver ACC1 after 7 mins by liquid scintillation counter				Bioorg Med Chem Lett 20: 2383-8 (2010) Article DOI: 10.1016/j.bmcl.2009.04.091 BindingDB Entry DOI: 10.7270/Q22N52DW
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