null
SMILES: O[C@H]1CCC[C@@H]1N1CCC(CC1)c1[nH]nc(c1-c1ccncn1)-c1ccc(Cl)cc1
InChI Key: InChIKey=UFZFALKWYRNPQE-PMACEKPBSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 11 (Homo sapiens (Human)) | BDBM50315120 ((1S,2S)-2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting | Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50315120 ((1S,2S)-2-(4-(3-(4-chlorophenyl)-4-(pyrimidin-4-yl...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting | Bioorg Med Chem Lett 20: 2634-8 (2010) Article DOI: 10.1016/j.bmcl.2010.02.047 BindingDB Entry DOI: 10.7270/Q21N818H | |||||||||||
More data for this Ligand-Target Pair |