BDBM50315215 3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-6-morpholino-1,3,5-triazin-2-yl)-8-oxa-3-azabicyclo[3.2.1]octane::CHEMBL1089219

SMILES: FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CC2CCC(C1)O2)N1CCOCC1

InChI Key: InChIKey=VTWMWRJHQXVFGY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315215   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Rattus norvegicus)	BDBM50315215 (3-(4-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)...) Show SMILES FC(F)c1nc2ccccc2n1-c1nc(nc(n1)N1CC2CCC(C1)O2)N1CCOCC1 |TLB:16:18:25:21.22| Show InChI InChI=1S/C21H23F2N7O2/c22-17(23)18-24-15-3-1-2-4-16(15)30(18)21-26-19(28-7-9-31-10-8-28)25-20(27-21)29-11-13-5-6-14(12-29)32-13/h1-4,13-14,17H,5-12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISA				Bioorg Med Chem Lett 20: 2644-7 (2010) Article DOI: 10.1016/j.bmcl.2010.02.045 BindingDB Entry DOI: 10.7270/Q2HQ402X
					More data for this Ligand-Target Pair