BDBM50315335 4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]pyrimidine-8-carboxylic acid::CHEMBL1089167

SMILES: CNC1CCN(C1)c1ncnc2c3cc(ccc3oc12)C(O)=O

InChI Key: InChIKey=WGTFQISCWQAIJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50315335 (4-(3-(methylamino)pyrrolidin-1-yl)benzofuro[3,2-d]...) Show SMILES CNC1CCN(C1)c1ncnc2c3cc(ccc3oc12)C(O)=O Show InChI InChI=1S/C16H16N4O3/c1-17-10-4-5-20(7-10)15-14-13(18-8-19-15)11-6-9(16(21)22)2-3-12(11)23-14/h2-3,6,8,10,17H,4-5,7H2,1H3,(H,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Argenta Discovery Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]histamine dihydrochloride from human histamine H4 receptor after 2.5 hrs by scintillation proximity assay				Bioorg Med Chem Lett 20: 2516-9 (2010) Article DOI: 10.1016/j.bmcl.2010.02.097 BindingDB Entry DOI: 10.7270/Q2CN74V3
					More data for this Ligand-Target Pair