BDBM50315475 CHEMBL1091606::N-(4-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindolin-7-yl)acrylamide

SMILES: FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=NZCUOOWQAWCQOB-VZUCSPMQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315475   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315475 (CHEMBL1091606 | N-(4-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H15Cl3F2N2O4S/c25-16-7-9-18(10-8-16)36(34,35)30-21(32)11-5-14-2-1-3-19-22(14)31(23(33)24(19,28)29)13-15-4-6-17(26)12-20(15)27/h1-12H,13H2,(H,30,32)/b11-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315475 (CHEMBL1091606 | N-(4-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H15Cl3F2N2O4S/c25-16-7-9-18(10-8-16)36(34,35)30-21(32)11-5-14-2-1-3-19-22(14)31(23(33)24(19,28)29)13-15-4-6-17(26)12-20(15)27/h1-12H,13H2,(H,30,32)/b11-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair