BDBM50315487 3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindolin-7-yl)-N-(3,4-difluorophenylsulfonyl)acrylamide::CHEMBL1091621

SMILES: Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)cc1F

InChI Key: InChIKey=HBQSKGKZQVEGBQ-WEVVVXLNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315487 (3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)cc1F Show InChI InChI=1S/C24H14F6N2O4S/c25-17-7-4-13(10-19(17)27)12-32-22-14(2-1-3-16(22)24(29,30)23(32)34)5-9-21(33)31-37(35,36)15-6-8-18(26)20(28)11-15/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315487 (3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)cc1F Show InChI InChI=1S/C24H14F6N2O4S/c25-17-7-4-13(10-19(17)27)12-32-22-14(2-1-3-16(22)24(29,30)23(32)34)5-9-21(33)31-37(35,36)15-6-8-18(26)20(28)11-15/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair