BDBM50315488 CHEMBL1091622::N-(3,4-dichlorophenylsulfonyl)-3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindolin-7-yl)acrylamide

SMILES: Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)cc1F

InChI Key: InChIKey=JXMBKNUVVVOUKU-WEVVVXLNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315488 (CHEMBL1091622 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)cc1F Show InChI InChI=1S/C24H14Cl2F4N2O4S/c25-17-7-6-15(11-18(17)26)37(35,36)31-21(33)9-5-14-2-1-3-16-22(14)32(23(34)24(16,29)30)12-13-4-8-19(27)20(28)10-13/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair