BDBM50315507 3-(3,3-bis(hydroxymethyl)-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-(4,5-dichlorothiophen-2-ylsulfonyl)acrylamide::CHEMBL1089780

SMILES: OCC1(CO)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1

InChI Key: InChIKey=JQUYKNPBPPJYBH-ZHACJKMWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315507   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315507 (3-(3,3-bis(hydroxymethyl)-1-(naphthalen-2-ylmethyl...) Show SMILES OCC1(CO)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C28H22Cl2N2O6S2/c29-22-13-24(39-26(22)30)40(37,38)31-23(35)11-10-19-6-3-7-21-25(19)32(27(36)28(21,15-33)16-34)14-17-8-9-18-4-1-2-5-20(18)12-17/h1-13,33-34H,14-16H2,(H,31,35)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	243	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315507 (3-(3,3-bis(hydroxymethyl)-1-(naphthalen-2-ylmethyl...) Show SMILES OCC1(CO)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C28H22Cl2N2O6S2/c29-22-13-24(39-26(22)30)40(37,38)31-23(35)11-10-19-6-3-7-21-25(19)32(27(36)28(21,15-33)16-34)14-17-8-9-18-4-1-2-5-20(18)12-17/h1-13,33-34H,14-16H2,(H,31,35)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair