BDBM50315518 3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide::CHEMBL1093790
SMILES: Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2C(=O)C(=O)N(Cc3ccc4ccccc4c3)c12
InChI Key: InChIKey=SPKOMQWURCMAAK-ZHACJKMWSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50315518 (3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17.4 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum | Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50315518 (3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer | Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG | |||||||||||
More data for this Ligand-Target Pair |