BDBM50315519 3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-yl)-N-(thiophen-2-ylsulfonyl)acrylamide::CHEMBL1089806

SMILES: CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccs1

InChI Key: InChIKey=GNMUUZLIIOWGJN-CSKARUKUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315519   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315519 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccs1 Show InChI InChI=1S/C23H18Cl2N2O4S2/c1-14-18-5-2-4-15(8-10-20(28)26-33(30,31)21-6-3-11-32-21)22(18)27(23(14)29)13-16-7-9-17(24)12-19(16)25/h2-12,14H,13H2,1H3,(H,26,28)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor (Homo sapiens (Human))	BDBM50315519 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccs1 Show InChI InChI=1S/C23H18Cl2N2O4S2/c1-14-18-5-2-4-15(8-10-20(28)26-33(30,31)21-6-3-11-32-21)22(18)27(23(14)29)13-16-7-9-17(24)12-19(16)25/h2-12,14H,13H2,1H3,(H,26,28)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair