BDBM50315523 CHEMBL1089161::N-(3-chlorophenylsulfonyl)-3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-yl)acrylamide
SMILES: CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1
InChI Key: InChIKey=RJHMXYMCSIQMML-PKNBQFBNSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50315523 (CHEMBL1089161 | N-(3-chlorophenylsulfonyl)-3-(1-(2...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer | Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E2 receptor (Homo sapiens (Human)) | BDBM50315523 (CHEMBL1089161 | N-(3-chlorophenylsulfonyl)-3-(1-(2...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a | n/a |
deCODE Chemistry Curated by ChEMBL | Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum | Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG | |||||||||||
More data for this Ligand-Target Pair |