BDBM50315603 2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amine::CHEMBL1093313

SMILES: Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1

InChI Key: InChIKey=ZQSNZROOZBSWNB-UHFFFAOYSA-N

Data: 4 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315603   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM50315603 (2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,...) Show SMILES Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C14H10N6O2/c15-12-17-14(22-9-5-2-1-3-6-9)18-13-16-11(19-20(12)13)10-7-4-8-21-10/h1-8H,(H2,15,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Heptares Therapeutics Limited Curated by ChEMBL					Assay Description Displacement of radioligand from human adenosine A2A receptor				J Med Chem 54: 4283-311 (2011) Article DOI: 10.1021/jm200371q BindingDB Entry DOI: 10.7270/Q23N23RZ
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50315603 (2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,...) Show SMILES Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C14H10N6O2/c15-12-17-14(22-9-5-2-1-3-6-9)18-13-16-11(19-20(12)13)10-7-4-8-21-10/h1-8H,(H2,15,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from adenosine A2A receptor in rat striatal membrane				Bioorg Med Chem 18: 2524-36 (2010) Article DOI: 10.1016/j.bmc.2010.02.039 BindingDB Entry DOI: 10.7270/Q2P84C13
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50315603 (2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,...) Show SMILES Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C14H10N6O2/c15-12-17-14(22-9-5-2-1-3-6-9)18-13-16-11(19-20(12)13)10-7-4-8-21-10/h1-8H,(H2,15,16,17,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	489	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Displacement of [125I]-I-AB-MECA from human adenosine A3 receptor expressed in CHO cells				Bioorg Med Chem 18: 2524-36 (2010) Article DOI: 10.1016/j.bmc.2010.02.039 BindingDB Entry DOI: 10.7270/Q2P84C13
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50315603 (2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,...) Show SMILES Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C14H10N6O2/c15-12-17-14(22-9-5-2-1-3-6-9)18-13-16-11(19-20(12)13)10-7-4-8-21-10/h1-8H,(H2,15,16,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.72E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Displacement of [3H]R-PIA from adenosine A1 receptor in rat cerebral cortex membrane				Bioorg Med Chem 18: 2524-36 (2010) Article DOI: 10.1016/j.bmc.2010.02.039 BindingDB Entry DOI: 10.7270/Q2P84C13
					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50315603 (2-(furan-2-yl)-5-phenoxy-[1,2,4]triazolo[1,5-a][1,...) Show SMILES Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1 Show InChI InChI=1S/C14H10N6O2/c15-12-17-14(22-9-5-2-1-3-6-9)18-13-16-11(19-20(12)13)10-7-4-8-21-10/h1-8H,(H2,15,16,17,18,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.42E+3	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-stimulated adenylyl cyclase activity				Bioorg Med Chem 18: 2524-36 (2010) Article DOI: 10.1016/j.bmc.2010.02.039 BindingDB Entry DOI: 10.7270/Q2P84C13
					More data for this Ligand-Target Pair