BDBM50315812 2-Amino-4-(4'-benzyloxy-3-chlorobiphenyl-4-yl)-2-(phosphoryloxymethyl)butanol::CHEMBL1090223

SMILES: NC(CO)(CCc1ccc(cc1Cl)-c1ccc(OCc2ccccc2)cc1)COP(O)(O)=O

InChI Key: InChIKey=GBCJASGKMQEDNP-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 3 (Homo sapiens (Human))	BDBM50315812 (2-Amino-4-(4'-benzyloxy-3-chlorobiphenyl-4-yl)-2-(...) Show SMILES NC(CO)(CCc1ccc(cc1Cl)-c1ccc(OCc2ccccc2)cc1)COP(O)(O)=O Show InChI InChI=1S/C24H27ClNO6P/c25-23-14-21(7-6-20(23)12-13-24(26,16-27)17-32-33(28,29)30)19-8-10-22(11-9-19)31-15-18-4-2-1-3-5-18/h1-11,14,27H,12-13,15-17,26H2,(H2,28,29,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human S1P3 receptor expressed in CHO cells assessed as intracellular calcium mobilization				J Med Chem 53: 3154-68 (2010) Article DOI: 10.1021/jm901776q BindingDB Entry DOI: 10.7270/Q2HH6K7W
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human))	BDBM50315812 (2-Amino-4-(4'-benzyloxy-3-chlorobiphenyl-4-yl)-2-(...) Show SMILES NC(CO)(CCc1ccc(cc1Cl)-c1ccc(OCc2ccccc2)cc1)COP(O)(O)=O Show InChI InChI=1S/C24H27ClNO6P/c25-23-14-21(7-6-20(23)12-13-24(26,16-27)17-32-33(28,29)30)19-8-10-22(11-9-19)31-15-18-4-2-1-3-5-18/h1-11,14,27H,12-13,15-17,26H2,(H2,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.60	n/a	n/a	n/a	n/a
Mitsubishi Tanabe Pharma Corporation Curated by ChEMBL					Assay Description Agonist activity at human S1P1 receptor expressed in human Chem1 cells assessed as intracellular calcium mobilization				J Med Chem 53: 3154-68 (2010) Article DOI: 10.1021/jm901776q BindingDB Entry DOI: 10.7270/Q2HH6K7W
					More data for this Ligand-Target Pair