BDBM50315892 CHEMBL1090355::phenyl 3-(5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)imidazo[2,1-b]thiazol-6-yl)phenylcarbamate

SMILES: O=C(Nc1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1)Oc1ccccc1

InChI Key: InChIKey=VRTJYLZXQJQCPQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50315892 (CHEMBL1090355 | phenyl 3-(5-(2-(4-morpholinophenyl...) Show SMILES O=C(Nc1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1)Oc1ccccc1 Show InChI InChI=1S/C32H27N7O3S/c40-32(42-26-7-2-1-3-8-26)35-24-6-4-5-22(21-24)28-29(39-17-20-43-31(39)37-28)27-13-14-33-30(36-27)34-23-9-11-25(12-10-23)38-15-18-41-19-16-38/h1-14,17,20-21H,15-16,18-19H2,(H,35,40)(H,33,34,36)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of ErbB2 by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair
Insulin-like growth factor I receptor (Homo sapiens (Human))	BDBM50315892 (CHEMBL1090355 | phenyl 3-(5-(2-(4-morpholinophenyl...) Show SMILES O=C(Nc1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1)Oc1ccccc1 Show InChI InChI=1S/C32H27N7O3S/c40-32(42-26-7-2-1-3-8-26)35-24-6-4-5-22(21-24)28-29(39-17-20-43-31(39)37-28)27-13-14-33-30(36-27)34-23-9-11-25(12-10-23)38-15-18-41-19-16-38/h1-14,17,20-21H,15-16,18-19H2,(H,35,40)(H,33,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair