BDBM50315904 4-(6-(3-nitrophenyl)imidazo[2,1-b]thiazol-5-yl)-N-phenylpyrimidin-2-amine::CHEMBL1093235

SMILES: [O-][N+](=O)c1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccccc2)n1

InChI Key: InChIKey=IWHRJPQDFJDKQC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50315904 (4-(6-(3-nitrophenyl)imidazo[2,1-b]thiazol-5-yl)-N-...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C21H14N6O2S/c28-27(29)16-8-4-5-14(13-16)18-19(26-11-12-30-21(26)25-18)17-9-10-22-20(24-17)23-15-6-2-1-3-7-15/h1-13H,(H,22,23,24)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of ErbB2 by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50315904 (4-(6-(3-nitrophenyl)imidazo[2,1-b]thiazol-5-yl)-N-...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nc2sccn2c1-c1ccnc(Nc2ccccc2)n1 Show InChI InChI=1S/C21H14N6O2S/c28-27(29)16-8-4-5-14(13-16)18-19(26-11-12-30-21(26)25-18)17-9-10-22-20(24-17)23-15-6-2-1-3-7-15/h1-13H,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant IGF1R expressed in Sf21 cells by time resolved fluorescence assay				Bioorg Med Chem Lett 20: 2452-5 (2010) Article DOI: 10.1016/j.bmcl.2010.03.015 BindingDB Entry DOI: 10.7270/Q2M908VT
					More data for this Ligand-Target Pair