BDBM50315967 CHEMBL1092432::N-(3,4-difluorophenylsulfonyl)-3-(2-(2-(naphthalen-2-yl)ethoxy)-4-((pyridin-3-yloxy)methyl)phenyl)propanamide

SMILES: Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1

InChI Key: InChIKey=LIBMRMOJDPGDBB-UHFFFAOYSA-N

Data: 4 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50315967   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315967 (CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50315967 (CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level after...				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Mus musculus (Mouse))	BDBM50315967 (CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Mus musculus (Mouse))	BDBM50315967 (CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Mus musculus (Mouse))	BDBM50315967 (CHEMBL1092432 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)CCc1ccc(COc2cccnc2)cc1OCCc1ccc2ccccc2c1 Show InChI InChI=1S/C33H28F2N2O5S/c34-30-13-12-29(20-31(30)35)43(39,40)37-33(38)14-11-26-10-8-24(22-42-28-6-3-16-36-21-28)19-32(26)41-17-15-23-7-9-25-4-1-2-5-27(25)18-23/h1-10,12-13,16,18-21H,11,14-15,17,22H2,(H,37,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by scintillation counter				Bioorg Med Chem Lett 20: 2639-43 (2010) Article DOI: 10.1016/j.bmcl.2010.02.034 BindingDB Entry DOI: 10.7270/Q23B6099
					More data for this Ligand-Target Pair